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Using this model, a significant drop in FDG tumoral uptake was observed 2 weeks after administration of 5 mg/week of fulvestrant (a tenfold higher dosage), with treatment beginning 23 days after tumor implantation.
The phenotypes were observed 2 weeks later.
The peak geometric mean concentration (GMC) of anti-rPA antibodies was observed 2 weeks after the second vaccination and diminished over time to low, but detectable, levels by the final study visit.
This functional benefit was already observed 2 weeks post-injection (data not shown).
Infusion-related neurofibrillary tangle pathology was first observed 2 weeks post-infusion and increased in a stereotypic, time-dependent manner.
No immunopositivity for Sox-9 in these injected cells, however, was observed 2 weeks or 4 weeks post injection.
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No cytotoxic effects were observed 3 weeks after implantation, and cells grew and aligned to the patterned GelMA strands.
A lumbar ganglionectomy designed to interrupt most sympathetic axons emanating from L2 IML caused 92% loss of ChAT-positive cells observed 10 weeks later at that site.
Bony fusion was observed 4 weeks after the end of distraction (Fig. 1).
Tunnel enlargement was already observed 6 weeks after ACL reconstruction [6].
Although after 2 weeks of the MCD diet no fibrosis was observed, 4 weeks of a MCD diet induced weak fibrosis and liver fibrosis was clearly observed at 6 weeks [25].
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