The Novartis trial, which began in 2008 in Europe with data analysis completed this year, was too brief to observe effects on basic intelligence.
For highly efficacious BSV, we observe effects on transmission, particularly at high transmission settings (Figure 1b, d, f).
By this setting up, we determined that 104 bacteria per amoeba was the optimal dose to observe effects on growth with β-tubulin targeting.
The QCA data obtained within the study enable us to observe effects on the extent of atherosclerosis.
It is possible that a longer treatment duration or contrast in risk factor levels between the groups is required to observe effects on cognition.
They did not observe effects on known estrogen-responsive transcripts; however, because HEECs are ERα negative and express ERβ, responses might reflect, in part, ERβ targets.
Thus, the apparent relation between study quality and observed effect on FMD should be interpreted with caution.
In addition, Munc18, but not Munc13, regulates growth cone filopodia, potentially via its previously observed effect on filamentous actin.
This observed effect on allelic fraction is, however, a combination of tumor purity and ploidy that is difficult to separate using only ~150 germline variants per patient.
First, they were observing effects in the context of tumor formation and progression, while we observed effects on cells that had already come from fully developed tumors.
