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To extend these observations to normal skeletal muscle we used PGC-1α transgenic mice on the GAA+/− background (tgGAA+/−) as controls; GAA+/− mice are phenotypically, morphologically, and biochemically normal.
As more and more structures are determined by structural consortiums worldwide, our ability to use this information in the identification of novel substrates of proteases in general will become more reliable and such information can be very vital in eliminating experimental artifacts and to extrapolate in vitro observations to normal physiological conditions.
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The Anderson Darling test was used to examine the fit of observations to a normal distribution.
Multivariate statistical analysis requires that the observations conform to normal distribution and the data transforms, such as log-transform (Cloutier et al. 2008), rank-ordered (Miller et al. 1997) and normalization (Ravichandrana et al. 1996; Ruiz et al. 1990), are carried out before doing multivariate statistical analysis.
While previous studies have examined whether insulin resistance is associated with older age (11, 12), they either limited their observations to only normal-weight subjects, or they did not objectively account for physical fitness or physical activity.
A presurgical assessment was performed, consisting of a general observation to assess normal weight, body conformation, and behavior.
Bird's list of 52 plates was developed using normal observations to determine plate boundaries, and relative motions described instantaneous rotation parameters.
From these findings we can conclude that, even though the exact impact is heavily dependent on specific use cases, conditional observation can be considered a useful extension to normal observation.
It therefore remains unclear to which extent the observations can be translated to normal STN function.
The notification criteria are similar to normal observation.
The basic concept of such systems is similar to normal observation where subscribers register at publishers (notifiers) and get responses depending on the original request made by the subscribers [8].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com