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The attachment of maleimide-functionalized microbeads to wounds created in live wild-type and diabetic mice led to observations of differential immobilization of microbeads on them and were consistent with anticipated differences in the presentation of sulfhydryl groups on the two different wound types.
The importance of looking beyond just polyA RNA is highlighted by our observations of differential expression with many non-coding and histone RNAs in total RNA.
Although the observations of differential hippocampal and amydalar LTP are interesting, these data should be interpreted carefully as the numbers of animals used in these studies are small.
Our observations of differential, time-dependent sensitivity of fluid uptake to Latrunculin versus Jasplakinolide, as well as dependence of the process on Cdc42, suggest the requirement for a highly dynamic population of actin for mediating pinocytic entry.
These observations are consistent with our previous observations of differential allelic response following KCl depolarization.
This is consistent with the previous observations of differential regulation of VIP1 expression during plant development as well as in response to various stimuli.
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The selection of DSC1 and DSG1 was based on their reported functionality in epidermal differentiation while DHRS7C was selected based on the observation of differential expression in the microarray HvS contrast and its location within the genome region reported to contain the Scurs locus [ 7].
After 2 weeks of exposure to 26 °C, no Hsp70 induction was detected, but an increase in protein damages indicated a lower resistance in shallow populations corroborating the previous observation of differential resistance capacity between deep and shallow populations of E. singularis, with a higher thermotolerance in deep populations.
This observation of differential expression has been confirmed by recent microarray experiments (John Wooton, personal communication).
Our observation of differential spermatogenic expression profile of G6pdx between two mouse species represented by Spr and B6 illustrates such a retroposition.
These overrepresented KEGG pathways and Gene Ontologies within the Carbohydrate Metabolism hypercluster reaffirm the initial observation of differential expression of carbohydrate metabolic genes, and begin to shed light on factors that may affect glycemic regulation in different ancestral populations.
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