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Observations A total of 105 patients were included in the study from 15th June 2007 to 15th September 2007.
The mothed was verified in the Zhangye Oasis during the first thematic experiment launched under the HiWATER project using extensive eddy correlation (EC) tower observations (a total of 16 EC towers) and multi-scale thermal infrared datasets, including aerial photos (3 m, as a bridge between the ground and satellite measurements), ETM+ (60-m resolution), ASTER (90 m), and MODIS (1000 m).
Secondly, the relatively small number of observations (a total of 128 patients) raised issues concerning sample representativeness.
Based on both observations, a total of 137 proteins were divided in six groups (I to VI, Figure 1 and Additional file 4).
According to PGF reference alignment observations, a total of 706 431 reads representing 78% of the 908 152 high-quality reads produced were located inside the specified MHC target region.
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In a total person-time of 355.2 person-years under observation a total of 849 transfers to acute hospitals have been observed.
During the 26 years of observation a total of 361,760 ADR-related hospitalizations were identified in the Netherlands (Table 2).
In this field observation, a total of 651 h of video recordings was made and used in data analysis.
Pooling data from both studies in order to compare HDI versus observation, a total of 713 patients were available for analysis with a median follow-up of 7.2 years.
At start of the observation, a total of 29% of the patients received steroids (42% systemic administration, 6% systemic and local intraarticular administration and 6% local intraarticular injections into the target joint only).Patients were treated with either DMARDs (49.4%) a combination of DMARDs plus biologics (14.7%) or biologic monotherapy (28.9%).
Since the frequency of the cumulative group of adverse pregnancy outcomes has an estimated frequency of 30% (unpublished observation), a total of about 1,000 pregnancies need to be evaluated to detect an absolute reduction of the frequency of 8% with allocation ratio 1 1, alpha error of 0.05, power of 80%.
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