Sentence examples for observation that reducing from inspiring English sources

These results, coupled with the observation that reducing Nodal signalling in Hex-AVE ablated embryos increases the frequency of phenotypes observed, suggests that these primitive streak patterning defects are due to defective Nodal signalling.

Loss of Pde6 activity increases OS Ca2+ levels possibly causing cell death, a conjecture supported by the observation that reducing Ca2+ influx by knocking out cGMP-gated cation channels (Cngb1 × Pde6β rd1 ) improves viability of rd1 rods.

The idea of this approach bases on the observation that reduced virus replication results in a reduced grouping (clustering) of infected cells.

The observation that reduced inter-chain coupling hardens Te Raman modes is explained by a competition between inter- and intra-chain forces in Ref. [23].

The indomethacin-induced generation of ROS also relates to the observation that reduced glutathione is depleted in the AML cells after treatment at different oxygen levels.

The observation that reduced FGF signalling results in hypoplasia of the cerebellar vermis in mice raises the possibility that reduced FGF signalling might underlie vermis hypoplasia in certain human conditions.

Our finding that Mig3 downregulates SIR2 provides a possible explanation for the observation that reduced Snf1 activity leads to accelerated aging in yeast [ 59], since Snf1 inhibits Mig3 [ 29].

Moreover, the observation that reduced MK apoptosis and platelet production were accompanied by a decrease in total ROS levels in the cells suggested that ROS were also involved in MK apoptosis to generate platelets.

The second reason derives from a simple observation that reduces the number of genotypes whose viability needs to be determined even more dramatically: Removal of a reaction from an unviable metabolism cannot result in a viable metabolism.

Moreover, these data confirm (and extend to HbA1c variability) our previous observation that reduced eGFR and, particularly, the nonalbuminuric CKD phenotype, in which an eGFR <60 mL/min/1.73 m develops in the absence of albuminuria, are not related to glycemic control (17).

The third mechanism is based on the observation that reduced ferredoxin is oxidized upon the addition of cysteine to IscS and postulates the presence of a stable persulfide radical intermediate that is transferred to IscU and then further reduced by iron to generate a ferric sulfide intermediate.