Using an "admission and/or observation" outcome as a less subjective index one might speculate that the elderly make better use of the PES than their younger counterparts (51% admission/observation rate versus 38% for those < 65).
These data are supported by the observation that outcomes are not significantly better, if at all, for reconstruction following traumatic ossicular discontinuity, [11, 12] a situation in which chronic infection and Eustachian tube dysfunction are not usually a factor.
1) The authors do not establish whether their observations regarding SOX2 are relevant to any important clinical observation or outcomes.
Thus in our main analyses we discarded the first two years of observation and outcomes detected during this period.
Specific points: 1) The authors do not establish whether their observations regarding SOX2 are relevant to any important clinical observation or outcomes.
One simple observation exists: outcomes are improved when care is coordinated by medical teams with experience, training, or decision support [ 1- 3].
Further longitudinal observation for outcomes which includes decline in pulmonary function, deterioration in muscle endurance, as well as the systemic inflammatory mediators may lead to useful measures to overcome detrimental changes in COPD patients.
Finally, a cross-sectional study design has several inherent weaknesses, such as lack of long-term observation for outcome and difficulty interpreting the association of exposure with outcome.
Observations of outcomes in clinical practice are a valuable adjunct to clinical trial results.
Comparing rows i and j in the data matrix B would provide n observations of outcomes from that Bernoulli process.
