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This is the key observation needed to establish a monotonicity result in the nabla setting.
In the longitudinal study of ten tumors in five mice (growths as in Fig. 6a), the uptake of [methyl-11C]-ZEGFR:2377-ST-CH3 equilibrated quickly when the tumors were small but was still increasing at 60 min when the tumors had grown larger (Fig. 6b, blue and green vs. red curves), which suggests that the time of observation needed until maximum uptake can vary with tumor development.
In over half of patients with fatal outcomes in our sample, death occurred with the first 72 h of observation needed to assess the response to treatment.
Before biologics were used, around 25% of all RA patients with 16 20 years of observation needed at least 1 large joint replacement (Wolfe and Zwillich 1998, Kapetanovic et al. 2008).
This important observation needed to be studied for extended time periods since a potentially lower mortality rate over time would be a strong indicator of the effectiveness of the EWA treatment programme.
This study indicated that a two-dose schedule of 4CMenB is sufficient in adults to provide robust immune responses against the vaccine antigens, although this observation needed to be confirmed in subjects whose occupation does not offer the possibility of priming through pre-exposure to a range of meningococcal strains.
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That observation needs additional study to confirm and understand it, Dr. Rossouw said.
Kazempour et al.'s experimental observation needs to be confirmed by more experiments.
This observation needs more detailed analysis of the distinct proteins which are involved in corona formation.
This observation needs, however, to be confirmed since both "AD-like" animals were females.
This observation needs further validation on a larger dataset as the current study contains only five Asian subjects.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com