This has driven, on the one hand, detailed quantitative observation of bridge models in the wind tunnel and, on the other, a steady development and refinement of parallel theory.
This paper describes patterns of reasoning that allow identity sentences to be grounded in sensory observations, thereby bridging the gap.
DOI: http://dx.doi.org/10.7554/eLife.04970.016 These observations suggest bridged H-NS may constrain ECs within a topologically closed domain that could promote pausing (see 'Discussion') but do not rule out the possibility that bridged H-NS binds DNA tighter than in linear H-NS filaments to create a stronger roadblock to transcript elongation.
Zhang et al. (2017) analyzed the kinematics of such a bright front in another light bridge observation by IRIS, and found parabolic trajectories of the bright front.
Prior to bridge observations, the outside of the hive was observed daily for 5 min to determine if marked bees were leaving the hive vicinity, or performing pre-foraging orientation flights in front of the hive.
A possible role in protein cross-linking is suggested by the observation that tyrosine bridges underlie the cross-linking of resilin [43].
For ChCODH, the observation that the bridging sulfide is displaced and the enzyme becomes inactivated by long exposures to CO (>20 h) prompted speculation that MtCODH/ACS and RrCODH structures lack the bridging sulfide due to CO inhibition (18).
Differentiating podocytes might also take a more direct route to the glomerulus [ 95, 104], on the basis of the observation of cell bridges or so-called tuft-to-capsule adhesions, where chains of cells link the glomerulus and capsule [ 105].
The relatively larger number of charged residues of HotAldO (Online Resource 4) is in agreement with the observation that salt-bridge networks are often responsible for thermostabilization of proteins (Karshikoff and Ladenstein 2001; Missimer et al. 2007).
Further, by measuring TMCP use in the primary care setting through direct observation, this approach bridges the gap between evidence-based strategies and implementation in the primary care setting [ 14].
While the number of charged residues in HotAldO (92) is higher than in AldO (78), in agreement with the observation that salt-bridge networks are often responsible for thermostabilization of proteins (Karshikoff and Ladenstein 2001, Missimer et al. 2007), it is unlikely that the relative amino acid content of the two proteins is solely responsible for the increased thermostability of HotAldO.
