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An HMM is a statistical model which models a generative time sequence characterized by an underlying hidden stochastic process generating an observable sequence [34].
The hidden Markov model (HMM) is a powerful statistical tool for modelling generative sequences that may be characterized by an underlying process generating an observable sequence.
The lack of observable sequence similarity has resulted in a widely held view that IRESs likely possess stable secondary structure allowing them to interact with the components of the translation machinery.
To investigate this further would involve extensive cloning and resequencing of the repaired amplicons, which is beyond the scope of this study, although comparison of the qPCR dissociation curves from extracts both before and after repair hints at the fact that no observable sequence differences exist.
Structure conservation constrains evolutionary sequence divergence, resulting in observable sequence patterns.
SCOP first organizes domains into families if domains have a common origin supported by observable sequence resemblance.
Similar(52)
Where these features were not observable, sequences at the 3'-end of the ESTs were used for designing primers to avoid long introns and target less-conserved 3' UTRs.
This confirms the previously acknowledged limitations of using TEM to examine for presence of phages and suggests that there may be several instances where there may be cryptic prophage elements in strains may be common but only observable from sequence data.
The s value coming from siz1m is designed to be dependent on the lengths of observable σ sequences, such that long sequences (on which the method performs well) are given high scores and utterly short sequences (where the method sometimes is wrong) are given low scores.
However, given the fully-observable nature of the CRFs [ 12], the observed sequences must be re-labelled to obtain a bijection between states and labels.
It is shown that the regime-switching approach based on MSAR models significantly outperforms those based on observable regime sequences.
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CEO of Professional Science Editing for Scientists @ prosciediting.com