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Similar observations held true for recognition of the 3F peptide by SLY-10 for which MIP1-β, RANTES and MIP1-α release were reduced by the CD8-null mutation (Fig. 3A F), whereas no IFN-γ, TNF-α or IL-2 were produced in the obsence of MHCI/CD8 interaction (Fig. 3G L).
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