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Drugs were omitted either because insufficient susceptibility data were available (that is, PAS, LZD, CFZ and BDQ) or because the mechanism of action remains obscure and SNPs to predict resistance have yet to be systematically identified (for example, cycloserine).
Though the general models discussed here do not answer all of our questions, their value lies in their ability to generalize and unify special case models, and to give us insights into the mechanics of evolution that can be obscured by the assumptions necessary to predict the long term behavior of particular model systems.
Afterwards, the tracking information is utilized to predict if the sun will be covered or obscured by clouds within the prediction horizon.
Cation exchange can thus obscure attempts to hindcast stored road salt sodium water table concentration from monitoring well sample stoichiometry, or to predict sodium impacts on groundwater or receiving stream quality downgradient of the well.
AG Ellinger, an investment adviser, explains his use of charts to predict stock price performance: "People think stocks and shares go up and down because of obscure reasons about companies.
Despite extensive efforts that focused on the development of computational models to predict in vivo cartilage behavior, and its application to clinical diagnosis and prognosis, substantial aspects nonetheless remain obscure.
"We tried to predict.
How? Hard to predict.
It is impossible to predict.
It's hard to predict.
It's impossible to predict.
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