Sentence examples similar to obligatory specifications from inspiring English sources
Blimp1 is obligatory for PGC specification but it does not appear to be required for the derivation or the maintenance of pluripotent ESCs or of Blimp1−/− epiSCs.
Thus, although Blimp1 is obligatory for PGC specification, it is not required for the reversion of epiSCs to ESCs and for their maintenance thereafter.
Our study shows that whereas Blimp1 is obligatory for PGC specification, it is dispensable during the derivation of ESCs and epiSCs, as well as during the reversion of epiSCs to ESCs and their long-term maintenance thereafter as self-renewing pluripotent stem cells.
Published: July 5 , 2012Expression of Blimp1, the key regulator of PGC specification, is obligatory for the establishment of the germ cell lineage in mice (Ohinata et al., 2005; Vincent et al., 2005).
Because of a bigger role of consultants and less involvements of experts of Rijkswaterstaat in the highway designing process, guidelines become much more obligatory and nowadays contain specific minimum values and other specifications of the highway elements.
In the example shown in Fig. 2, the obligatory parameter would be the format specification, while the change coordinate file, ChSys, serves as an option.
The Constitution, drawn up to Mr. Chavez's specifications last year, makes the teaching of "Bolivarian ideology" obligatory in all schools.
► Knockout of Blimp1 has no effect on derivation or maintenance of ESCs or epiSCs ► Blimp1 is not required for reversion of epiSCs to an ESC state ► Blimp1 is required for PGC specification ► Transit through a PGC state is not obligatory for acquisition of pluripotency Bao et al.
Another advantage of RBF is that extensive parameter specification is un-obligatory for this function.
