Sentence examples for obligatory component of the from inspiring English sources

Nicastrin is an obligatory component of the γ-secretase; the enzyme complex that leads to the production of Aβ fragments critically central to the pathogenesis of Alzheimer's disease (AD).

An obligatory component of the dissemination process is the obtaining of a "motile phenotype".

An obligatory component of the homo sovieticus mentality was the placing of collective interests above personal ones; individuals were appreciated by their contribution to the common good.

Great hopes were raised by the discovery that the PTP is inhibited by CsA [49 51], but it is now clear that CyPD is a key modulator but not an obligatory component of the PTP.

In view of this evidence, the three obligatory components of the EMPOWER-PAR intervention were designed based on four interrelated CCM elements, namely organisation of health care, delivery system design, self-management support and decision support.

When conducting microarray analyses of cellular responses to stimuli, it is often difficult to distinguish genes that are obligatory components of the cell's response from genes that are induced only in particular cell types or under certain conditions, and may therefore be less critical to the outcome of the response.

The major distinction between the two criteria is that the IDF criterion specifies an obligatory component of central obesity, which is optional in the NCEP ATP-III criterion.

The observation that the Fur protein, ferric uptake regulator [ 82], is controlled by the respiratory regulators is not unexpected, because iron is an obligatory component of most respiratory complexes [ 2] and the transcriptional factor Fnr itself [ 83].

Given that the NR1 subunit is an obligatory component of functional NMDA receptors (Mayer and Armstrong 2004; Monyer et al. 1994), we focused on NR1 subunit in this study.

The internal check (peer review) is an obligatory component of any radiological service today.

An illustrative comment was 'I believe ALS training should be an obligatory component of undergraduate training… I did not get this opportunity and felt thoroughly unprepared in some situations during my first job in acute medicine' (09 04).