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Retrieved studies were evaluated in terms of objectives, diseases studied, data sources, methodologies and performance for real-time surveillance.
We reviewed and described the articles in terms of objectives, diseases studied, data sources, methodologies, and performance for real time surveillance.
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It records ailments based on objective diseases, but is particularly sensitive to health complaints with minimal or no clinical findings.
Effects on symptom severity are very promising, and further research examining effects on objective disease severity and treatment adherence is warranted.
More generally, Katon et al [38] have concluded that symptoms of depression and anxiety are associated with greater symptom burden (net of objective disease severity) in a variety of conditions, including chronic lung disease, diabetes, heart disease and arthritis, suggesting that the patterns described here are relevant to adaptation.
Patients must have shown objective disease progression at study entry.
Objective disease progression was observed in 68 patients.
Alzheimer's dementia syndromes, like all neurodegenerative diseases, lack objective disease- and stage-specific biomarkers [ 34].
Objective disease responses have been documented in five different tumor types.
In future research this should be addressed and more objective disease characteristics should be included.
Patient amelioration was confirmed by a marked, persistent improvement in both subjective and objective disease activity.
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