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With the objective of clarifying the mechanism of Schiff base formation, we characterized the binding of quinate and shikimate to the wild-type and K170M mutant DHQD using ITC, NMR, and X-ray crystallography.
While quinate and shikimate complexes were pursued with the objective of clarifying the noncovalent basis of substrate and product binding, it may be more instructive to view protomer A binding in the context of analyzing the carbinolamine intermediates.
With the objective of clarifying the possible direct role of EPO on hepcidin regulation, we analyzed the dose-dependent effect of EPO on hepcidin levels on freshly isolated mouse hepatocytes and on the human hepatocyte cell line HepG2, which express endogenous hepcidin, EPO, and EPOR.
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This highlights the importance of clarifying the objectives of PHC evaluation before choosing an evaluative instrument.
Objective To clarify associations of fish consumption and long chain omega 3 fatty acids with risk of cerebrovascular disease for primary and secondary prevention.
Objective: To clarify the role of physiologic regulators of bone turnover in patients with anorexia nervosa (AN).
Study Objective: To clarify the efficacy of the lightwand technique compared with that of the conventional laryngoscopic technique for awake endotracheal intubation in patients requiring emergency surgery.
In fact, understanding the effects of glucose on MSCs does not only represent a main objective to clarify the pathophysiology of hyperglycemia.
Objective To clarify the effect of the using the intrauterine device on fertility in nulliparous women.
Objective: To clarify the cause of HBV replication, we investigated genotype differences and mutations in the core promoter and precore region in relation to virus titer.
Objective: To clarify the role of chymase produced from mast cells in adhesion formation, we measured chymase activity level and investigated the preventive effect of a chymase inhibitor, Suc-Val-Pro-Phep OPh 2, on the poSuc-Val-Pro-Phep OPh 2ormation.
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objective of determining
objective of identifying
objective of discovering
objective of confirming
objective of investigating
purpose of clarifying
objective of informing
objective of defining
goal of clarifying
objective of establishing
objective of demonstrating
objective of describing
intention of clarifying
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com