Sentence examples for objective of a trial from inspiring English sources

When the primary objective of a trial involves more than one efficacy endpoints it is desirable to extend the two-stage design to a setting that accommodates two hypotheses while controlling overall type I and II errors (α and β).

If the primary objective of a trial is to learn about the ability of a new treatment to help future patients without sacrificing the safe and effective treatment of the current patients, then a Bayesian design with frequent assessments of the accumulating data should be considered.

Result interpretations also vary depending on the nature of non-compliance and the objective of a trial.

Volunteers may continue to participate in research because of their personal aspirations which may not necessarily relate to the objectives of a trial.

The main objective of a pilot trial is to provide sufficient assurance to enable a larger definitive trial to be undertaken.

The objective of a phase II trial should, in addition to identifying active therapies, be extended to identifying those that are likely to be successful in pivotal trials.

Articles were selected to include only studies that had chronic cancer pain as the primary or secondary objective of a controlled clinical trial.

The objective of a non-inferiority trial is to demonstrate the efficacy of an experimental treatment not being inferior to a reference treatment by some pre-specified non-inferiority margin.

For our review, we examined 68 journal articles published between 1999 and 2002 that had chronic cancer pain as the primary or secondary objective of a controlled clinical trial.

The variation of the maximum RVbleed/stroke(i) according to the different CHADS2 and HEMORR2HAGES scores is depicted in figure 3. The objective of a non-inferiority trial is to show that the effect of a new treatment on a target outcome is not worse, compared with an established effective treatment (EET), by more than a prespecified margin.

The objective of a phase I trials in paediatrics is to determine the recommended dose of a new treatment in children while evaluating its toxicity.