Recently, Russell Katz, a neurologist and the director of the primary Food and Drug Administration division that oversees the Alzheimer's clinical trials, said that "an effective therapy for early Alzheimer's disease would need to make an objective impact in the lives of the afflicted".
The authors received external funding to provide an objective impact evaluation of the program.
Objective: Impact of the interval between interruption of aspirin intake and surgery on postoperative bleeding and transfusion in coronary artery bypass graft (CABG), with extracorporeal circulation (ECC).
This might strike us as peculiar: statistics should tell us the objective impact that the data have on a hypothesis, but here the impact seems to depend on the sampling plan of the researcher and not just on the data themselves.
To investigate the objective impact of green buildings on health, we tracked IEQ, self-reported health, and heart rate in 30 participants from green and conventional buildings for two weeks.
Turning to the objective impact of emotional distraction on WM performance, the present findings suggest that the actual impact of anxiety-inducing distracters on WM performance is also linked to bottom-up effects.
Brain activity was recorded using event-related fMRI while healthy participants performed this WM task, and behavioural assessment involved measures indexing the subjective and objective impact of distraction on cognitive performance, as well as measures of personality traits (i.e., trait anxiety).
This finding provides strong support for the idea that the objective impact of emotional distraction in this task is mainly linked to bottom-up effects, in which enhanced perceptual processing of the anxiety-inducing angry face distracters may divert attention from the main WM task and impair performance.
Therefore, the main goal of the present investigation was to examine the brain mechanisms mediating the subjective and objective impact of transient anxiety-inducing distracters on cognitive performance, and the role of individual variations in trait anxiety affecting the sensitivity to emotional distraction.
72 Thus, the objective impact on patient safety is inconclusive, but the perceived impact suggests patient safety has declined.
