Exact(11)
The strengths of the trial include ABPM (as the objective endpoint), independent outcomes assessment, and therapeutic use of spironolactone.
The focus of the study was on mortality as an objective endpoint.
The primary outcome measure being an objective endpoint such as a defined reduction or gain in a physiological parameter.
In an oncology clinical trial, an objective endpoint is survival and a subjective endpoint is a symptom score.
However this association appears to be greatest for the subjective endpoints, and more modest for the objective endpoint.
Foradil, Nexium, and Frova followed similar patterns, where the nonprimary PRO endpoint provided key support to a clinical, objective endpoint.
Similar(49)
Further studies should be employed to address long-term outcomes and should include objective endpoints.
However, this was probably unlikely as we found a good agreement between these criteria and our objective endpoints, particularly for ETI success and time.
No large studies have directly assessed patient satisfaction related to the treatment of migraine in primary care, partly because there are no objective endpoints for pain which is, by its nature, subjective.
In order to avoid bias and not confound data interpretation, the use of objective endpoints and blinding patients, study staff, core labs, and clinical endpoint committees to treatment assignment are helpful approaches.
The only objective endpoints that can be validated are disease-free survival or overall survival.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com