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The RESPOND study met its primary objective, demonstrating that patients with multiple organ dysfunction and protein C deficiency have greater improvements in protein C with alternative therapy (higher dose and/or variable duration) compared to standard drotrecogin alfa (activated) therapy.
Figure 7 (right) shows projection of a volume acquired with the low NA objective, demonstrating simultaneous visualization of all of the refractive surfaces of the anterior segment, from the anterior surface of the cornea to the posterior surface of the lens.
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Interestingly, corresponding higher resolution images (63×, numerical aperture 1.4) of a subset of the data taken with the 40× objective demonstrated a similar shift toward larger mitochondrial volumes in the DPN group as well as the DM group.
Candidates must also "demonstrate a positive learning environment that supports and challenges students;" "show active engagement of students in their own understanding of the concepts, skills, and/or processes related to the learning objectives;" demonstrate how they are "deepening student understanding;" and provide a "subject-specific pedagogical focus".
A recent study of FBA models with different objectives demonstrates that under nutrient scarcity a FBA model with the maximization of the biomass yield objective achieve the highest predictive accuracy, while maximizing the ATP or biomass yield per average flux unit is the best objective for unlimited growth on glucose under aerobic conditions [ 22].
Objective: Demonstrate the importance of the use of ultrasonography for the evaluation of the polytraumatized patient.
Data for the secondary objective of demonstrating faster recovery in Caucasian subjects after sugammadex vs neostigmine were analyzed as for the primary objective.
While affordability was taken into consideration, the main objective was demonstrating that: "You can live large in a small space".
SMART-1 is the first ESA Small Mission for Advanced Research in Technology, with the prime objective of demonstrating the use of Solar Electric Primary Propulsion in a planetary mission.
The primary objective of demonstrating equivalent exposure to bosentan in paediatric and adult PAH patients was not met.
For bimatoprost, fondaparinux, peginterferon alfa-2a, peginterferon alfa-2b and tipranavir, the objective of demonstrating superiority was realised.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com