Sentence examples for numerous tumor types from inspiring English sources

Increased heparanase expression was found in numerous tumor types and correlates with poor prognosis.

FASN expression increases with tumor progression and associates with chemoresistance, tumor metastasis, and diminished patient survival in numerous tumor types.

Gambhir's team appears to have found a way to force any of numerous tumor types to produce a biomarker whose presence in the blood of mice unambiguously signifies cancer, because none of the rodents' tissues — cancerous or otherwise — would normally be making it.

Misexpression of imprinted genes is associated with many diseases including numerous tumor types, growth dysplasias, neurological conditions, and several pregnancy-associated disorders [2] [8].

S100A4, a small Ca2+-binding protein of the S100 family, is an essential pro-metastatic mediator in tumor and is categorized as a useful prognostic marker in numerous tumor types [4], [5].

OXPHOS and glycolysis have been evaluated in numerous tumor types, including renal clear cell carcinoma (RCC) in which the majority of glycolytic enzymes are overexpressed and mitochondrial enzymes underexpressed relative to patient-matched normal kidney cortex [6].

Furthermore, overexpression of MnSOD has shown to inhibit cellular proliferation of numerous tumor cell types both in vitro and in vivo (31, 50, 61).

Its sales are modest right now, but Novartis hopes to make it into a billion-dollar best seller by getting it approved in numerous other tumor types, including breast cancer, stomach cancer, lymphoma and certain rare types of pancreatic tumors.

BLM is somatically mutated in ∼4.2% of CRCs as well as numerous other tumor types, including breast, lung, prostate, and ovarian (Table S1), and the relevance of therapeutically targeting SOD1 within these tumors warrants further study.

Survivin is expressed in proliferating cells such as embryonic and fetal cells and is undetectable in differentiated normal tissue; however, survivin is highly expressed in numerous solid tumor types including colon, breast, lung and liver, and its expression is associated with aberrant cell survival and tumor progression [ 18- 20].

HHIP antagonizes all three of the hedgehog family of ligands (SHH, DHH and IHH) and has been shown to be down-regulated in numerous epithelial tumor types [ 59] with the notable exception of basal cell carcinoma where it is upregulated [ 60].