The receptors targeted by each drug the PPAR-γ receptor and the GLP-1 receptor, respectively are widely distributed in numerous tissues with as yet ill-defined roles.
Infections can be found in numerous somatic tissues as well as the gonads [ 15].
Although the biological functions of CD133 remain unknown [7], CD133 alone or in combination with other markers is currently used to isolate stem cells from numerous tissues [4], [5], as well as the prostate [8], liver [9] and pancreas [10], [11].
Indeed, CD133 alone or in a combination with other markers is currently used for the isolation of stem cells from numerous tissues, such as bone marrow, brain, prostate, liver, pancreas Uchida et al. 2000; Salven et al. 2003; Sugiyama et al. 2007; Shmelkov et al. 2008), and both developing and adult kidney (along with CD24)(Sagrinati et al. 2006; Lazzeri et al. 2007).
Using SAGE method, previous studies have characterized the transcriptome of numerous tissues such as uterus [ 7], adipose tissue [ 8, 9], skeletal muscle [ 10], hypothalamus, cerebral cortex and pituitary gland [ 11, 12].
B-cell translocation gene 2 (belongselongs to the anti-proliferative gene family, whose expression is deregulated in carcinogenesis of numerous tissues such as prostate, kidney, breast, liver and brain.
Recent use of more rigorous lineage tracing tools have strongly called into question the ability of epithelial cells to transition into collagen-producing mesenchymal cells during repair processes in numerous tissues, such as the kidneys [ 63- 65], liver [ 66- 68] and lungs [ 69].
In humans, PBDEs have been detected in numerous tissues, with serum concentrations reported as high as 50 ng/g lipid (Petreas et al. 2003).
Background: In biomedical research, the past two decades have seen the advent of in vitro model systems based on stem cells, humanized cell lines, and engineered organotypic tissues, as well as numerous cellular assays based on primarily established tumor-derived cell lines and their genetically modified derivatives.
DDX21 was found to localize to the nucleus and nucleolus in a number of breast cancer tissues as well as in numerous established breast cancer cell lines.
