Sentence examples for numerous tissue types from inspiring English sources

Since numerous tissue types require the support of stromal fibroblasts to provide appropriate cross-talk and ECM production to maintain tissue homeostasis and enable repair, the fibroblast cells that we derived have great potential for applications in regenerative medicine [35].

Degradation of the ECM through catabolic processes can result in the generation of a variety of matrix protein fragments with the potential to influence cellular behavior in numerous tissue types, usually with a detrimental outcome [ 9, 11, 12, 31- 33].

For example, calmodulin, the predominant Ca2+ sensor, plays a critical role in decoding Ca2+ signatures into proper cellular responses in numerous tissue types and cellular compartments in eukaryotes [ 41].

Brg1 is required in numerous tissue and cell types in vivo (Ho and Crabtree, 2010), including multiple cell types within the cardiac lineage (Hang et al., 2010; Stankunas et al., 2008; Takeuchi and Bruneau, 2009; Takeuchi et al., 2011).

DTTs have been shown to induce the expression of a variety of ARE-associated detoxification enzymes and molecules, including GCLC and GSH, in numerous cell and tissue types; however, limited information is available regarding the activities of these interesting molecules in the CNS [23 25].

Thus numerous cell / tissue types can be affected.

Thus, roles for RANKL/RANK signaling have been found in bone, mammary tissue, the immune system, and CNS, suggesting pleiotropic effects on numerous cell and tissue types.

The Wnt signaling is crucial for the proper development of numerous cell and tissue types, as well as for maintenance of adult stem cell populations [144].

The particular dynamic conditions in the RCCS bioreactor have been shown to favour the differentiated phenotype expression for numerous cell and tissue types [ 13, 24, 29– 31].

It is well known that while some genes may exhibit rather narrow ranges of expression across tissues and cell types, many genes exhibit expression across numerous tissues and cell types [ 37, 38].

Although a relatively large and heterogenous sample set was used, numerous tissues and cell types are un- or under-represented by this dataset.