Sentence examples for numerous substrates from inspiring English sources

Upon activation, AMPK phosphorylates numerous substrates to regulate glucose uptake, mitochondrial biogenesis and gluconeogenesis suppression.

The great number of dehydrogenases available makes the concept applicable for numerous substrates to analyse.

Enzyme-mediated modification sites on numerous substrates could be revealed by large-scale proteomic analysis of enriched peptides.

They possess a high redox potential (1.1 1.2 V) so that numerous substrates can serve as electron donors (Liers et al. 2013a).

Many transporters have multi-specificity towards numerous substrates thus the clinical outcomes for transporters like aforementioned ABCG2 may reflect only a portion of their physiological function (Table 1).

Inhibition of GSK3 by lithium has multiple effects on cellular functions due to the numerous substrates of GSK3, any of which may contribute to the mood stabilizing action of lithium.

The present study was designed to investigate expression and activity of P-gp and of multidrug resistance-associated protein (MRP), another ABC efflux pump sharing numerous substrates with P-gp, in human monocyte-derived DC.

Phosphorylated Akt is responsible in activating and de-activating phosphorylation of numerous substrates.

Once activated, PKB phosphorylates numerous substrates influencing diverse cellular and physiological processes attributed to the PI3K pathway [12].

However, while numerous substrates for the mammalian cell death-associated caspases have now been described, few caspase substrates have been identified in other organisms.

Cdk5 has specifically been implicated in exocytosis and endocytosis via phosphorylation of numerous substrates including synapsin, amphiphysin I, dynamin, and others [44] [47].