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As a result, case-control association studies have identified numerous significantly associated susceptibility loci, but lack of replication among studies is widespread [3], [4], [8], [15] [18].
By comparing expression in females and males at E6 numerous significantly sexually dimorphic genes not previously implicated in gonad development were identified.
Our data show that numerous significantly regulated genes associated with apoptosis are involved in NF-κB signalling pathway and MAP kinase signalling pathway.
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We identified numerous miRNAs significantly associated with patient prognosis in different smoking status groups or in LUAC in general (Table 2 and Additional file 14).
The salivary gland libraries from Brevirostrata ticks contained numerous contigs significantly similar to silks of true spiders (17 and 8 in, respectively, R. microplus and R. sanguineus), whereas the Longirostrata tick contained only 4 contigs.
Additionally, the proteomic response to a second stress differed with p CO2, with numerous processes significantly affected by mechanical stimulation at high versus low p CO2 (all proteomics data are available in the ProteomeXchange under the identifier PXD000835).
Significantly numerous members of the precariat realise today that there is no such thing as a level playing field.
As a result of these reforms, the number of state-owned businesses declined significantly; numerous interests such as utilities companies, banks, tourism-sector entities, and other enterprises had been privatized by the early 2000s.
The constitution of Poland's postwar socialist state, the Polish People's Republic, took effect in 1952 but was amended numerous times, most significantly in early 1989, when constitutional reforms worked out between the government and Solidarity were passed by the Sejm (legislature).
They also qualify for numerous incentives, which significantly lower their total cost of ownership compared to gas guzzlers.
The challenges facing the radiologist in imaging assessment of penetrating trauma of the neck and face are numerous and impact significantly on the effective management of these patients in the acute setting.
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