Sentence examples for numerous signalling molecules from inspiring English sources

In its role as a scaffolding protein, caveolin-1 is capable of recruiting numerous signalling molecules as well as regulating their activity [13], [14].

Matrix metalloproteinases are not only able to cleave all the constituents of ECM proteins, but also to activate or deactivate other numerous "signalling" molecules, such as receptors, adhesion molecules and growth factors [ 1, 5, 9, 10].

Zinc is an essential trace element functioning as a catalytic cofactor for multiple enzymes; and it is required to maintain the expression and structure of numerous signalling molecules and transcriptional regulators, many of which are involved in cancer growth and metastasis (Dufner-Beattie et al, 2003; Juhasz et al, 2003; Wang et al, 2002).

Most patients with autosomal dominant polycystic kidney disease (ADPKD) harbor mutations in PKD1, the gene for polycystin-1 (PC1), a transmembrane protein with a cytoplasmic C-terminus that interacts with numerous signaling molecules, including Gα12.

Numerous signaling molecules and reactions participate in the NFkB signaling pathway [33].

Numerous signaling molecules control the maintenance of DCs in peripheral tissues [27].

Numerous signaling molecules could potentially serve as a read out of coincidence detectors, but prominent in neurons are those that comprise the Mitogen Activated Protein Kinase (MAPK) signaling cascades, which include several distinct kinases that are critical for normal neuronal function [9].

The PSD contains glutamatergic receptors, N-methyl-D-aspartic acid (NMDA), alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPA), the group I metabotropic glutamate receptors (mGluRs) and numerous signaling molecules [22], [23].

DOI: http://dx.doi.org/10.7554/eLife.06828.001 During development, cells send and receive numerous signaling molecules.

Activated RTK phosphorylates numerous signaling molecules that initiate the intracellular signaling cascades leading to cell proliferation and survival [ 12].

Focal adhesion kinase (FAK) is one of the numerous signaling molecules present in focal adhesion sites [ 42].