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Numerous regulatory pathways have been found to participate in an ever-growing signaling pathway network in dendritic spines [5], [6], [9], [10].
Numerous regulatory pathways are implicated in the transduction of hypertrophic signaling.
They transduce signals received by the heptahelical G-protein coupled receptors (GPCRs) from outside the cell and impact numerous regulatory pathways via their respective effectors, which in turn effect activity of secondary messengers [ 20, 21].
Research into the molecular basis of body weight regulation has increased exponentially in recent years, following the discovery of an increasing number of relevant hormones, peptides and other signaling molecules, allowing numerous regulatory pathways to be elucidated (Huda et al., 2006; O'Rahilly et al., 2003; Schwartz and Morton, 2002).
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Numerous metabolic and regulatory pathways are regulated during long-term acclimation to high temperature in D. pulex.
It has been demonstrated that the depletion of polyamines can lead to cell cycle arrest or apoptosis by affecting numerous cell cycle regulatory pathways [ 34].
Moreover, phosphorylation levels for numerous regulatory sites in these pathways were significantly changed due to PPP1R12A knockdown.
In the present study, to characterize cucurbitacin I, we evaluated its effects on proliferation and growth regulatory pathways in numerous human leptomeningeal, grade I and II meningioma cell cultures.
In addition, SNPs were identified in 21 lignin pathway genes, 20 genes involved in cell wall precursor pathways and in numerous regulatory genes including various transcription factor families, signalling genes and hormone genes.
Alterations in expression of a limited number of genes may influence the dysregulation of numerous, integrated immune response, cell signaling and regulatory pathways that are common to a number of SAID.
The ubiquitin-proteasome system (UPS) regulates the degradation of numerous regulatory proteins that control signal transduction, cell cycle progression and differentiation, as well as apoptotic pathways [1].
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