Sentence examples for numerous proteins such from inspiring English sources

Sirt1 can deacetylate numerous proteins such as tumor suppressor protein, p53, which modulates various genes that control damaged DNA [34].

For these reasons, albumin has been fused to numerous proteins such as interferon [ 9], interleukin-2 [ 10], butrylcholinesterase [ 11], coagulation factors VII [ 12] and IX [ 13, 14], hirudin [ 15, 16], and barbourin [ 17], as well as to smaller peptides [ 18].

Microtubule-associated proteins are among the protein clients of heat-shock proteins (HSP70 and HSP90), themselves associated with and stabilising numerous proteins such as HER2, AKT and the AR (Georget et al, 2002).

Numerous proteins such as LEAFY COTYLEDON 1 (LEAFY, LEAFY COTYLEDON 2 (LEAFY, LEAFY COTYDELDON 1 LIKE (L1L), WUSCHEL (WUS), PLANT GROWTH ACTIVATOR 37 (PGA 37) and AINTEGUMENTA-LIKE 5 (AIL5) have all been shown to induce SE when overexpressed [ 12, 18- 21].

(21) Nonspecific ligands such as heparin and alginate sulfate employ electrostatic affinity interactions present on numerous proteins;(22) such ligands, when added to hydrogel systems, have been utilized to govern release of many growth factors, including bFGF, 23) NGF, 24) VEGF, PDGF-BB, and TGFβ1.

The acute response to stress causes the release of catecholamines from the chromaffin cells of the adrenal medulla accompanied by numerous proteins, peptides such as chromogranin A (CGA) and its natural fragments.

Recent data show that beside G proteins numerous other proteins, such as β-arrestins and kinases, may interact with GPCRs and activate intracellular signalling pathways.

This multiprotein complex includes numerous intracellular proteins such as syntrophin, dystrobrevin and dystrophin downstream of dystroglycan (DG) [19], [20].

They all share a central protein/protein interaction PDZ domain and appear to bind to numerous membrane proteins such as Semaphorins [9],α-Integrins [10], [11], the Insulin Receptor [12], [13], the Human Leutropin Receptor [14], the β1-Adrenergic Receptor [15] and some Frizzleds [6].

Functionally speaking, CD44 is involved in organ integrity through its ability to contact ECM, is signalling active, and serves as a co-receptor for numerous transmembrane proteins such as matrix metalloproteases, members of the ERB family of receptor tyrosine kinases, and the long-known tumour-associated antigen EpCAM (CD326, ESA1) [5].

Numerous cytoplasmic proteins, such as tubulin and heat shock protein 90, can be (de)acetylated, altering their function.