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The molecular mechanisms of HDL/SR-BI induced signaling revealed the involvement of numerous pathways that mediate the atheroprotective actions of HDL in cells relevant to atherogenesis such as macrophages, endothelial cells, and vascular smooth muscle cells.
For any franchisor pondering whether to expand into Dubai (and the rest of the Middle East), there are invariably numerous pathways that can lead you to what is often called the city of the future.
However, these methods may find numerous pathways that are independently represented.
Numerous pathways that promote cell proliferation are activated by the binding of various ligands to cell surface receptor tyrosine kinases (RTKs).
A common end to numerous pathways that lead to defective sperm function is attributed to reactive oxygen species (ROS), a group of molecules with incompletely reduced oxygen atom [ 10, 11] that are capable of reacting with almost all biomolecules leading to their altered function such as inhibition/activation of enzymes.
But numerous pathways that they do retain require ATP, begging the question: where is their energy from?
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There are numerous other pathways that promote [1, 3, 20] and oppose [13, 21] centrosome separation during bipolar spindle formation.
Advances in molecular biology have increased our understanding of the numerous molecular pathways that may contribute to prostate carcinogenesis.
A line of evidence has been provided that phosphatases play an important role in numerous signaling pathways that regulate cell proliferation, apoptosis, adhesion, and migration [ 6].
OP-1 regulates numerous metabolic pathways that are not only limited to its well-documented anabolic function, but also to its anti-catabolic activity.
The complex molecular machinery of autophagy makes its regulation further complicated, and involves numerous signaling pathways that might also interact at multiple levels.
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