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145, 146 Numerous pathways have been identified and insulin sensitivity has been considered a key factor for healthy aging.
Numerous pathways have been suggested to promote macrophage apoptosis within plaques although a dominant mechanism seems to be the induction of endoplasmic reticulum stress.
The non-canonical signalling pathway is essentially an umbrella term for all Wnt-activated cellular signalling pathways that do not promote β-catenin-mediated transcription, and numerous pathways have been identified.
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Furthermore, while the specific glycolipid flippases involved in numerous biosynthetic pathways have been identified, and in some cases structurally characterized17, 18, there remains little information regarding the translocation of C55-P to the cytoplasmic face of the inner membrane1.
Numerous regulatory pathways have been found to participate in an ever-growing signaling pathway network in dendritic spines [5], [6], [9], [10].
These findings have promoted the view of yeast as an evolutionarily distant model of metazoan apoptosis and numerous orthologous pathways have since been reported.
Numerous metabolic pathways have been implicated in diabetes-induced renal injury, yet few studies have utilized unbiased systems biology approaches for mapping the interconnectivity of diabetes-dysregulated proteins that are involved.
Numerous signalling pathways have impacts on DCs.
Numerous neurobiological pathways have been implicated in the etiology of suicide and suicidal behaviour.
Numerous signaling pathways have been implicated in the regulation of apoptosis of breast cancer cells and several reports have suggested a link between radiation- or chemotherapy-induced apoptosis of breast cancer cells and activation of death receptor pathways (8– 10).
Numerous neurotransmission pathways have been found to be dysfunctional in schizophrenia, which raises the probability that membrane phospholipids that modulate the activity of both receptors and are involved in signal transduction may be part of the etiology of schizophrenia.
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