Sentence examples for numerous pathways are from inspiring English sources
Numerous pathways are affected by aberrant DNA hypermethylation, including cell cycle, DNA repair, and hormonal responses, and therefore alter the perfect epigenetic cell equilibrium.
The enrichment analysis revealed that in aged WT mice, in spite of the histologically confirmed full wound closure (Day 21), numerous pathways are still significantly activated as compared to the intact skin (Table 1, Suppl. Table 2).
The same mediators that cause general inflammation and harm in sepsis are required for host defence, numerous pathways are highly redundant, and receptors that distinguish self from non-self are also needed for the recognition of danger signals.
The process of counterion exchange, association of the boronic acid and subsequent dihedral rotation was not calculated (i.e., from VII to the pre-transmetallation complex), because numerous pathways are possible and it is unlikely that the free-energy barriers for this process are higher than the competing β-hydride-elimination barrier of 115 kJ mol−1.
Experimental testing of hundreds of targets from numerous pathways is not feasible.
Numerous pathways were enriched by down-regulated genes; the most significant ones were the insulin, Wnt and integrins signaling pathways, MAPK, cytokine-cytokine receptor interaction, tight junction and focal adhesion, all representing proteins that are highly expressed in malignancies.
145, 146 Numerous pathways have been identified and insulin sensitivity has been considered a key factor for healthy aging.
Numerous pathways have been suggested to promote macrophage apoptosis within plaques although a dominant mechanism seems to be the induction of endoplasmic reticulum stress.
The non-canonical signalling pathway is essentially an umbrella term for all Wnt-activated cellular signalling pathways that do not promote β-catenin-mediated transcription, and numerous pathways have been identified.
Numerous regulatory pathways are implicated in the transduction of hypertrophic signaling.
Such systems approaches are critical, as metabolism itself is a molecular transformation process where numerous metabolic pathways are inextricably interlinked [ 4].
