Sentence examples for numerous pathogenic pathways from inspiring English sources

The important roles of the CXCL12/CXCR4 axis in numerous pathogenic pathways involving HIV infection and cancer metastasis make the CXCR4 receptor an attractive target for the development of therapeutic agents.

SL1067 is a potent tool for studying various processes in which IL-1α is engaged but the specifics remain undefined, e.g., Caspase-1 dependent IL-1α secrethen59, the potential for IL-1α/IL-1RI complex to function as an autocrine growth factor38, and the regulation of functional IL-1α activation by IL-1RII in necrosis17, as well as its role in numerous pathogenic pathways.

From this joint effort, major pathogenic pathways emerged.

Cordell, H.J. et al. International genome-wide meta-analysis identifies new primary biliary cirrhosis risk loci and targetable pathogenic pathways.

Globotriose is involved in numerous pathogenic processes and drug development strategies.

Preeclampsia is a complex syndrome with variable phenotypes that suggest differing underlying pathogenic pathways.

As epiregulin is EGFR ligand and HOXB9 is its transcriptional inducer, we suggest that the main molecular link between miR-215-5p miR-215-5p miR-215-5ppes presents the EGFR signandng pathway, whiCRCis one of the cellsical phenotypes presents in CRC.

Using bacterial toxins, we describe a new approach for discovering broad-spectrum therapies capable of inhibiting host proteins that mediate multiple pathogenic pathways.

Cellular senescence has evolved to restrict tumor progression but the accompanying senescence-associated secretory phenotype (SASP) promotes pathogenic pathways.

The improvement of the knowledge of these interrelationships should contribute to elucidate pathogenic pathways and design effective treatments for NAFLD.

Aryl hydrocarbon receptor knock-out exacerbates choroidal neovascularization via multiple pathogenic pathways.