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Recent years have seen continuous reports about the successful reconstruction of numerous organs with the application of tissue‐engineering techniques.
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The reason is that the hypothalamus interacts with numerous organs and tissues, driving alterations of homeostasis.
Tuberous sclerosis complex (TSC) is an inherited hamartoma disease with tumor growth in numerous organs.
For carcinomas from numerous organs, high fascin expression levels are associated with increased invasiveness and earlier patient death (Machesky and Li, 2010).
It was reported that changes in methylation states of several genes induced by exposure to antiandrogen vinclozolin during the period of sex determination are correlated with disease state in numerous organs of adult rats, including prostate [ 5, 59].
Furthermore, there are also examples of lineages that have become, arguably, less complex with evolution (e.g., loss of numerous organs and body parts in parasites, loss of eyes in deep sea and cave-dwelling fauna).
The animal experiments evidenced the increase of ddI blood half life (3-fold) and its enhanced accumulation as prodrug form at 24 h in numerous organs and especially intestine after administration of ProddINP in comparison with free drug.
Mice with targeted deletion of RelB develop chronic inflammation of numerous organs secondary to an impaired ability to clear autoreactive T-cells.
We have tested this platform with Type 2 diabetes (T2D) model, which involves the malfunction of numerous organs such as pancreas, circulation system, liver, and adipocyte.
Since individual plants consist of numerous organs, generic models of organ growth applicable across species are desirable.
Our results support that interventions in the first months of life may not be appropriate with respect to the metabolic risk during such a window of plastic development of numerous organs.
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