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It was reported that changes in methylation states of several genes induced by exposure to antiandrogen vinclozolin during the period of sex determination are correlated with disease state in numerous organs of adult rats, including prostate [ 5, 59].
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Since individual plants consist of numerous organs, generic models of organ growth applicable across species are desirable.
Recent years have seen continuous reports about the successful reconstruction of numerous organs with the application of tissue‐engineering techniques.
Furthermore, there are also examples of lineages that have become, arguably, less complex with evolution (e.g., loss of numerous organs and body parts in parasites, loss of eyes in deep sea and cave-dwelling fauna).
Our results support that interventions in the first months of life may not be appropriate with respect to the metabolic risk during such a window of plastic development of numerous organs.
Bone morphogenetic protein (BMP) signaling is crucial for the development and function of numerous organs, but its role on the function of pancreatic islets is not completely clear.
Mice with targeted deletion of RelB develop chronic inflammation of numerous organs secondary to an impaired ability to clear autoreactive T-cells.
The endothelial-mesenchymal transition (EndMT) is a fundamental cellular mechanism that occurs under both physiological and pathological conditions and includes the fibrotic stages of numerous organs, namely, the skin, kidneys, heart, lungs and liver.
GATA4 is a member of the GATA family of transcriptional regulators that is required for the development and differentiation of numerous organs in the early embryo.
We have tested this platform with Type 2 diabetes (T2D) model, which involves the malfunction of numerous organs such as pancreas, circulation system, liver, and adipocyte.
Notch signalling is crucial for the correct development and growth of numerous organs and tissues, and when subverted it can cause cancer.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com