Sentence examples for numerous mutations of from inspiring English sources

However, it is often the case that numerous mutations of small effect contribute to fitness.

Numerous mutations of Merlin have been identified in Neurofibromatosis type 2 and other cancer patients.

An excellent example is familial partial lipodystrophy or Dunnigan syndrome, in which numerous mutations of the LMNA gene have been found.

Drosophila lines from natural populations contain a reservoir of genetic variation, with each line containing a unique combination of numerous mutations of small to moderate effect.

Whilst numerous mutations of the gene encoding cyt b, a mtDNA-encoded cIII subunit, have been associated with slowly progressive, usually adult onset, mitochondrial myopathy, mutations in nuclear genes associated with cIII deficiency are much rarer, and characterized by severe clinical course.

At a minimum, they should look at the numerous mutations (mostly loss-of-function, but some gain-of-function) that have been reported to extend longevity in yeast.

The mutator hypothesis was based on the observations of numerous mutations in different types of tumors, which could not be explained by the mutation rates of normal somatic cells.

In silico proficiency testing, which evaluates only the bioinformatics component of NGS assays, is a recently introduced PT method that allows for evaluation of numerous mutations spanning a range of variant classes.

It was thus interesting to see whether in spite of numerous mutations, the core region of HCV RNA could be expressed in mammalian cells.

Numerous mutations affecting components of the signal transduction chain for photon perception are known, some of them have an effect on photocurrent and its' kinetics (reviewed in 31).

However, the S288C allelic form of ABZ1 is located at the end of a long branch such that it appears to be the result of the accumulation of numerous mutations.