Sentence examples for numerous mutations at from inspiring English sources

This program models the evolution of genomic sequences in a population under the influx of numerous mutations at multiple loci and can take into account dozens of parameters/variables simultaneously.

Evolution in the opposite direction from a posibacterium would have required numerous mutations in at least dozens of genes to evolve a lipid, protein, and lipoprotein export machinery; as the closest negibacterial relatives of Endobacteria are Selenobacteria with the exceedingly complex lipopolysaccharide, this would also have had to evolve at that juncture!

In both phylogenies numerous mutations are located at tips of the network, and are derived from ancestral haplotypes at the interior nodes in the network.

Other mutated genes in breast cancer reported in the Catalogue of Somatic Mutations in Cancer (COSMIC) database [ 60] include PIK3CA (25% [ 61]), TP53 and CDH1 (22%), PTEN (6%), AKT1 (5%) and numerous mutations that occur at frequencies <5%.

At a minimum, they should look at the numerous mutations (mostly loss-of-function, but some gain-of-function) that have been reported to extend longevity in yeast.

As illustrated at Fig. 1, numerous mutations occur in a tissue with billions of cells constantly turning-over.

This is in the core 507 533 region, in which numerous mutations have been observed to cause resistance to RIF, although mutations at other sites in this region are more frequent (mutations specifically at Asp 435 constitute only 9% of all RIF-R cases).

Dr Damian Dowling, of Monash University who was one of the researchers, said the results point to numerous mutations within mitochondrial DNA that affect how long males live, and the speed at which they age.

One is to create numerous mutations in a single gene.

Directed evolution works by making numerous mutations in a gene that produces a particular protein.

But as scientists began discovering a much broader array of genetic mutations linked to cancer, oncologists needed a way to screen individual patients for numerous mutations.