Sentence examples for numerous mouse models from inspiring English sources

For functional analyses of specific roles of these systems, numerous mouse models have been generated which lack or overexpress individual signal transduction components.

By analyzing metabolic pathways in numerous mouse models of cancer and in human cancer samples transplanted into mice, the team found that the browning of white fat "was consistent in all of these models and led irreversibly to cachexia," says study co-author Erwin Wagner, a cancer biologist at CNIO. "This process is likely happening in these patients.

In order to study AD, numerous mouse models are available.

For further investigation, numerous mouse models for cancer biology are already available, and these resources can be productively mined to expand our understanding of cancer gene networks.

Numerous mouse models of squamous cell cancer have been developed including carcinogen-induced SCC, ultraviolet (UV) light-induced SCC and spontaneous SCC in various transgenic and knockout mouse strains.

Recent studies have shown that IL-10 producing B-cell subsets with varying phenotypes can regulate different immune responses in numerous mouse models, such as inflammatory bowel disease (IBD), EAE, type 1 diabetes, collagen-induced arthritis, contact hypersensitivity and during parasitic infection [5].

Despite the fact that active and passive immunisation against amyloid-β (Aβ) has been shown to clear or prevent Aβ brain plaques and improve cognitive performance in numerous mouse model studies [ 8], large-scale trials of several immunotherapeutics targeting Aβ have displayed little or no cognitive efficacy [ 6].

HER2 overexpression is potently transforming in numerous cell culture models and in numerous transgenic mouse models (Moasser, 2007a).

Immunization with CRCL generated from tumors elicits specific T and NK cell-dependent immune responses leading to protective immunity in numerous mouse tumor models.

CD4+CD25+FOXP3+ regulatory T cells (Treg) are of critical importance for the maintenance of immune homeostasis, as numerous experimental mouse models for autoimmune diseases correlate the presence of functional Tregs with amelioration of disease severity [1], [2].

Since then, numerous genetic mouse models have been generated.