Exact(7)
There are numerous molecules that have been evaluated for these purposes, but studies suffer from limitations of design, statistical rigor, and outcome measure.
Among the numerous molecules that are upregulated in CNS lesions (Sofroniew, 2009), chondroitin sulphate proteoglycans (CSPG) were examined first.
In keeping with these findings, our results revealed that TdEC express numerous molecules that are associated with the CNS or are implicated in brain differentiation and axon guidance.
This appeared to cause the transcription factors associated with these pathways such as NF- κB to promote the expression of their transcriptional targets, including numerous molecules that are themselves involved in TNF- α/IL-6 signalling.
Numerous molecules that mimic incretins or prevent them from being degraded are in clinical trials.
The migration process is regulated by cell-extrinsic signaling pathways and cell-intrinsic regulation and implicates numerous molecules that synergistically guide neuron motility.
Similar(53)
In order to uncover the richness of biological activities within existing chemical libraries, we performed a broad, phenotype-based screen on zebrafish embryos and identified numerous small molecules that perturbed a wide variety of different processes during development.
Additionally, perivascular localised mast cells secrete numerous vasoactive molecules that regulate BBB permeability [ 21, 22].
In the past few years, numerous intracellular molecules that negatively regulate LPS-activated signaling pathways have been discovered.
Activated RTK phosphorylates numerous signaling molecules that initiate the intracellular signaling cascades leading to cell proliferation and survival [ 12].
The numerous small molecules that are used for so-called "mitochondrial pharmacology" modulate various mitochondria-confined processes.
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