Sentence examples for numerous molecular pathways from inspiring English sources

Using the CNV model in mice and rats, our findings demonstrated the potency of Lodamin as a broad-spectrum antiangiogenic ophthalmic drug in inhibiting neovascularization, edema and inflammation by targeting numerous molecular pathways in addition to VEGF.

Numerous molecular pathways by which BPVs are able to transform urothelial cells are known to occur in vivo.

Advances in molecular biology have increased our understanding of the numerous molecular pathways that may contribute to prostate carcinogenesis.

The number of targets is so high that parkin protein results involved in numerous molecular pathways (proteasome-degradation, mitochondrial homeostasis, mitophagy, mitochondrial DNA stability, and regulation of cellular cycle).

The ERs are members of the steroid hormone nuclear receptor family of transcription factors, which are activated by specific steroid hormones and control numerous molecular pathways in hormone responsive tissues, including differentiation and proliferation (Ascenzi et al. 2006; Shang and Brown 2002).

Based on these previous and our current findings, we can hypothesize that APP metabolism is altered at an early stage of fetal development, and its degree of alteration may be one of the most significant, among numerous molecular pathways that are implicated in the development of DS phenotypes.

However, the numerous aberrations in molecular pathways that can produce cancer necessitate the use of drug combinations, as compared to single drug for treatment of individual cancers.

A wealth of research has begun to identify the genetic, epigenetic, neural, and environmental underpinnings of resilience, and has indicated that resilience is mediated by adaptive changes encompassing several environmental factors, neural circuits, numerous neurotransmitters, and molecular pathways.

In recent years, numerous molecular and metabolic pathways involved in plant responses and adaptation to various types of environmental stresses have been identified and reported.

Selenium compounds have been reported to affect numerous cellular events and molecular pathways leading to apoptosis.

Numerous agents specifically targeting dysregulated molecular pathways, believed to be key tumorigenic drivers, have recently been approved or are being evaluated as potential treatment options in patients with breast cancer or other tumor types [ 19].