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Although several functionalization methods using chelating agents have been suggested and developed [18 24], those methods have numerous limitations for nuclear molecular imaging because the radionuclides originally incorporated with chelating agents can detach from those molecules in vivo [25 27].
The TAVI devices designed for the treatment of calcific aortic stenosis have numerous limitations for the treatment of pure AR such as the risk of residual AR, the lack of repositionability and retrievability, and the need for valve- in-valve implantation.
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Numerous limitations of aortic valve grafts currently used in pediatric patients cause the need for alternative prostheses.
Numerous limitations of computational annotation were discussed.
There are numerous limitations of note in this study.
Numerous limitations of self-reports have been discussed such as social desirability and recall bias.
There were numerous limitations of the present study that need to be recognized.
There are numerous limitations of the early experiments that form our classical understanding of CSF physiology.
Numerous limitations exist, including the availability of funds for new projects, as well as restrictions within and between departments as to how the data they have gathered can be used.
Although analysis of intact serum/plasma is attractive, numerous limitations increasingly make this approach less suitable for metabolomics studies.
Nutritional studies are inherently difficult to conduct and are subject to numerous limitations such as variable composition and adherence for study diets, multiple nutrients changed, different outcome measurements for kidney disease, small sample sizes, and short duration of studies.
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