Exact(5)
Activation of blood coagulation in cancer is a complex phenomenon, involving many different pathways of the hemostatic system and numerous interactions of the tumour cell with other blood cells, including platelet, monocyte and endothelial cells.
Due to the numerous interactions of ϕ N in this system, there is potential for complex flux response behaviour.
The numerous interactions of three arginine residues from the Cv1693 insertion domain with the 5′-phosphate of AMP suggested that the true substrate would bind an AMP-like moiety in this pocket and contribute to substrate recognition.
Using this experimental model, we observed numerous interactions of mononuclear intravascular leukocytes with endothelial cells of capillaries, veins, and arteries during acute rejection, which seem to contribute to the pathogenesis of allograft vasculopathies [ 7, 9].
A systems approach to the study of biochemical networks requires the creation of models (and software to simulate them) that take into account the numerous interactions of chemical components of the whole system [ 2, 3].
Similar(55)
Sorting out the contributions of these numerous interactions to in vivo function requires structural information to enable use of point mutant FLNa or partners lacking specific activities that are otherwise fully functional.
Frataxin has been proposed to be a multifunctional protein based on its numerous interactions, including components of the Fe-S biosynthesis machinery, ferrochelatase, mitochondrial aconitase, succinate dehydrogenase, and several chaperones [2], [9] [12], [15].
The observation that CNCs are capable of numerous interactions suggests that some CNCs might participate in the co-regulation of groups of protein-coding genes in response to specific cellular signals.
Temperature is a key component in the ecology of DENV as seen from its numerous interactions with other components of the disease system.
The presence of numerous adipokine systems and the possibility of numerous interactions between them result in precise response to energetic and immunological balance changes and consequently in the precise regulation of organism homeostasis.
The second one presents a simplification of the comprehensive map by applying a method of reduction of the numerous interactions into modules without losing any content from the original map.
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