Sentence examples for numerous interaction partners from inspiring English sources

We interpret the observations that (i) domains which appear in the inner cores likely physically interact with (ii) a low average strength as follows: Domains with numerous interaction partners have an elevated chance of being fused in a higher eukaryote, while domains which interact frequently are less likely to be fused.

The functions of MICOS in mitochondrial membrane architecture and biogenesis are influenced by numerous interaction partners and the phospholipid environment.

Fulfilling the signal integration function requires differential networking of SLP65 with numerous interaction partners.

Indeed, numerous interaction partners for LNX proteins have been identified, but the in vivo functions of most family members remain largely unclear.

Finally, the four and a half LIM domain protein 3 (FHL3, LIS-spot 1418), which is down-regulated in our analysis, is an adaptor protein with numerous interaction partners.

Their argument is based in part upon the nature of networks; gene products that have numerous interaction partners (high node-degree) tend to be involved in any process you care to look at.

As numerous 14-3-3 14-3-3 14-3-3artners have been interactionin apartners and cell cycle regulation, it is not surprising thave14-3-3 proteins play a crucial role in carcinogenesis.

These modified genes permit numerous applications including assessment of protein expression pattern, identification of protein interaction partners by immunoprecipitation followed by mass spec, and reversible removal of the tagged protein in any tissue.

These proteins are either phosphorylated by BCR-ABL or promote phosphorylation of their interaction partners, which in turn triggers the activation of numerous signaling pathways, including RAS-RAF, MAPK, PI-3-Kinase, c-JUN and c-MYC pathways [ 7- 10].

The FRET signal is affected by numerous variables, e.g. the chosen fluorophores, sterical orientation of the fluorophores, expression and size of the fusion protein, quantity of interacting proteins and, finally, distance between both interaction partners [3], [4].

Using Ka, Ks and the Ka/Ks ratio as proxies, people have found significant correlations between protein evolutionary rates and numerous features derivable from genome sequences, such as the number of protein-protein interaction partners, gene expression levels, the essentiality of a gene and the number of paralogs of a gene [ 42- 44] (and papers cited therein).