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Clones #5 and #18 for example were characterized by low and high sensor activity, respectively, corresponding to the detection of 1 and numerous insertions in the two clones, respectively.
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For example, numerous insertions are present in the loop regions linking various α-helices (α10 to α13) in anticodon binding domain of P. falciparum TyrRSs (PF11_0181 and MAL8p1.125) when compared to its human homologous (2PID and 1N3L) respectively.
However, in all syntenic regions detected, the shared genes were separated by intervening genes reflecting the occurrence of numerous insertions and deletion of genes in both rice and Musa.
Sequence degradation may range from a single disabling mutation, such as a frameshift or an in-frame stop codon in a protein-coding gene, to extensive changes including numerous insertions and deletions [ 7, 16].
In clones of human keratinocytes carrying from a single to numerous insertions of the vitamin D3 sensor, a sensitive sensor read-out is detected upon exposure to even low concentrations of vitamin D3 analogues.
There are numerous insertions separating the above-mentioned conserved sequence stretches, but these insertions are often rich in amino acids that are likely to appear in loops and solvent-exposed regions [ 35].
These alignments also revealed numerous insertions and deletions among these loci.
Our multiple genome comparisons revealed that there were numerous insertions and deletions but no significant rearrangements.
Overall, the wAu and wMel genomes are similar, but with a significant amount of rearrangement.> Like wMel, there is a large amount of DNA corresponding to mobile genetic elements in the wAu genome, including numerous insertion sequence (IS) elements.
High levels of nucleotide substitution and numerous insertion-deletion events were detected within and between the two species.
It also contains numerous insertion sequence elements.
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