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These alignments also revealed numerous insertions and deletions among these loci.
Our multiple genome comparisons revealed that there were numerous insertions and deletions but no significant rearrangements.
The SSU rRNAs from this diverse taxon have been found to possess numerous insertions and extensions and our aim was to unravel their evolution.
Sequence degradation may range from a single disabling mutation, such as a frameshift or an in-frame stop codon in a protein-coding gene, to extensive changes including numerous insertions and deletions [ 7, 16].
However, in all syntenic regions detected, the shared genes were separated by intervening genes reflecting the occurrence of numerous insertions and deletion of genes in both rice and Musa.
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Clones #5 and #18 for example were characterized by low and high sensor activity, respectively, corresponding to the detection of 1 and numerous insertions in the two clones, respectively.
They are characterized by lower than average genomic G + C content, biased codon usage, as well as presence of numerous insertion elements and transposon relicts.
Apicomplexan proteins frequently contain numerous insertions relative to proteins from other species (Feng et al., 2006; Kissinger and DeBarry, 2011), a characteristic thought to result from various factors, including high AT genome content, DNA strand slippage, double strand break repair, high recombination rates, and selection pressure for parasite antigenic variation.
There are numerous insertions separating the above-mentioned conserved sequence stretches, but these insertions are often rich in amino acids that are likely to appear in loops and solvent-exposed regions [ 35].
For example, numerous insertions are present in the loop regions linking various α-helices (α10 to α13) in anticodon binding domain of P. falciparum TyrRSs (PF11_0181 and MAL8p1.125) when compared to its human homologous (2PID and 1N3L) respectively.
In clones of human keratinocytes carrying from a single to numerous insertions of the vitamin D3 sensor, a sensitive sensor read-out is detected upon exposure to even low concentrations of vitamin D3 analogues.
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