Exact(3)
In addition, growth factors, cytokines and chemokines mediate numerous important cellular functions.
The mitochondrion is an important organelle responsible for numerous important cellular functions in insects such as energy transduction, apoptosis, detoxification, signal transduction and ATP production [ 21, 22].
17 Telomeres are specialized protein-DNA structures at the ends of all linear chromosomes that play numerous important cellular roles, including the prevention of chromosome degradation and end-to-end chromosome fusions, 18 as well as the proper pairing, recombination, and segregation of chromosome homologs during meiosis.
Similar(57)
Over the past three to four decades, there have been numerous successful efforts in recognizing important cellular proteins essential in cancer growth and therefore these proteins have been targeted for cancer treatment.
Autophagy is an important cellular response to numerous diseases.
The use of isotopically labeled compounds has yielded numerous important insights into the workings of cellular and organismal metabolism.
This fatty acid appears to be an important cellular component because numerous proteins require myristoylation to exert their biological effects on transduction pathways, vesicular trafficking, and structural positioning [ 46].
Nitric oxide (NO) is an important cellular messenger involved in numerous physiological functions of the body.
Caspase-3 stands out among the known caspases, because it is commonly activated by numerous "death" signals and cleaves a variety of important cellular proteins [ 64].
Since oxidative stress has been implicated in numerous human diseases and conditions, the Keap1 Nrf2– ARE pathway has been become an important cellular target for the development of potential therapeutic and preventive agents for a number of diseases and conditions.
Mitogen-activated protein kinases (MAPKs) are a family of serine/threonine protein kinases involved in the early apoptosis that regulate important cellular processes such as cell survival and adaptation by phosphorylating numerous cytoplasmic and nuclear targets [ 5- 8].
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