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While we have attempted to focus on effects which exhibited consistency over multiple lags and/or diagnosis groups, we have nonetheless conducted numerous hypothesis tests, increasing the number of potentially false positive results.
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This resulted in numerous hypotheses being tested but most p-values were very low or very high, reducing the likelihood of incorrect inferences.
For all of these reasons, gene expression studies have the potential for testing numerous hypotheses (i.e., numerous "traits" or genes), many of which an investigator would not necessarily think to test from previous research.
False-positive results are common when testing numerous hypotheses, while false negatives are caused by poor statistical power.
The findings from this review regarding stakeholders' views and priorities for CRT service organisation and delivery can generate numerous hypotheses which could be tested in future research.
Utilizing a variety of genetic approaches, such as the candidate gene approach and Genome Wide Association Studies (GWAS), researchers have tested numerous hypotheses that focus on the inheritance of exceptional longevity, including inheritance of mitochondrial genes [ 8], somatic genes [ 6, 8], and x-linked genes [ 2, 9].
One challenge in testing the numerous hypotheses about serotonin's function has been observing the activity of identified serotonergic neurons in animals engaged in behavioral tasks.
Second, it is difficult to evaluate and/or control inference accuracy for such testing, which involves numerous hypotheses.
However, with regard to multiple hypothesis testing, our study was not sufficiently powered to investigate the numerous possible epistatic interactions between the genes investigated here.
"I've heard numerous hypotheses," Mr. Rosencranz said.
A startup is a hypothesis testing machine.
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