Sentence examples for numerous human malignancies from inspiring English sources

It has been found to be amplified, overexpressed, or constitutively activated in numerous human malignancies with oncogenesis derived from the simultaneous promotion of cell survival and suppression of apoptosis.

TICs have now been identified and characterized in numerous human malignancies.

High expression levels of the human DEK gene have been correlated with numerous human malignancies.

High expression levels of LETM1 have been correlated with numerous human malignancies.

The switch from cyclin D1a to cyclin D1b is observed in numerous human malignancies and is associated with poor prognosis.

Mutations in PTEN have been identified in numerous human malignancies, including cancers of the brain, endometrium, ovary, and prostate.

Dysregulation of miRNA has been well documented in nearly all types of human malignancies, and numerous miRNA are involved in tumor formation and progression by regulating the expression and action of many oncogenes and tumor suppressor genes.

The changes in the levels of miRNA expression have been observed in many human malignancies, and affected numerous pathways involved in apoptosis, proliferation, survival and invasion.

This survival tactic of cancer cells has been consistently creating numerous hurdles towards restorative therapy for a number of human malignancies.

Since their discovery almost three decades ago, numerous alterations in miRNA expression with varying underlying mechanisms were associated with human malignancies [ 1].

This might correspond with observations from numerous groups that telomerase activity correlates with the stage and grade of many human malignancies[ 9, 10].