Sentence examples for numerous histone modification from inspiring English sources

Among numerous histone modification enzymes studied a recurrent theme is that the enzymes or their associated protein complexes are capable of interacting with histones [ 37, 38].

The 'regulatory features' track in the 'region in detail' view reveal DNase I hypersensitive sites and numerous histone modification and methylation sites aligning to the 5'UTR and upstream region of MYO6 transcripts.

Numerous histone modifications include (not exclusively) acetylation, methylation, and phosphorylation.

Among numerous histone modifications, trimethylation of histone H3 lysine 9 (H3K9) is associated with chromatin compaction and decreased expression [ 31].

Numerous histone modifications are associated with different levels of gene expression, most prominently H3K4 trimethylation as an indicator of active transcription, and H3K27 trimethylation as an indicator of inactive genes.

Much of this complexity results from the presence of numerous histone post-translational modifications and histone variants.

In this context, numerous histone post-translational modifications (PTMs) have been described that include acetylation, phosphorylation, methylation, ubiquitylation and SUMOylation [ 1].

Observing numerous genes where histone modifications and transcripts co-vary was expected.

The analysis of cancer cells epigenomes also revealed numerous aberrations in histone modifications including histone acetylation and methylation.

However, this approach became limited in scope when performing experiments that aimed to identify histone modification profiles at numerous genomic loci or genome wide.

Epigenetic regulation based on histone modification is essential for numerous biological processes in eukaryotic organisms1,2.