Sentence examples for numerous genetic polymorphisms from inspiring English sources

These challenges may also be compounded by the rapid erythrocyte turnover and anemia in SCD, the heterogeneous multi-organ complications and the numerous genetic polymorphisms affecting disease severity, predisposition to specific phenotypes, the vast variation in response to HU treatment and the overall clinical course of the disease [60].

Numerous genetic polymorphisms have been reported to be associated with CKD and kidney function.

The susceptibility to sepsis and organ dysfunction in trauma patients might be the result of a combination of numerous genetic polymorphisms.

Mild reductions in endolysosomal degradative capacity may be caused by numerous genetic polymorphisms as well as an increased degradative load in various degenerative disorders characterized by intracellular accumulations.

Advances in sequencing technologies allow whole genomes to be sequenced more economically and efficiently than ever before, providing an excellent opportunity to discover numerous genetic polymorphisms in a genome and for quantitative trait locus (QTL) analysis and marker-assisted selection.

Numerous studies evaluated the effect of genetic polymorphisms on responses to air pollution exposures in both animals and humans.

Identification of glioma risk factors has also proven to be extremely challenging, despite numerous studies on environmental exposures and genetic polymorphisms [ 1, 4, 5].

In the post-genome era, numerous genetic variations such as single nucleotide polymorphism (SNP) and rare variant have been discovered in international genomic projects such as the International HapMap Project [ 1- 5], the ENCODE Project [ 6- 8], and the 1000 Genomes Project [ 9, 10].

Numerous studies have explored the potential role of genetic polymorphisms as predictive or prognostic biomarkers in gynecologic malignancies.

Whereas numerous studies have examined the effect of specific genetic polymorphisms on disease susceptibility and severity, relatively little attention has been paid to their direct impact on parasite gene expression patterns within the host.

Studies on the contribution of genetic polymorphisms to cancer development have examined numerous genes, including oncogenes, tumor suppressors, DNA repair genes and those encoding Phase I and Phase II enzymes [ 4].