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AHLs in Clade-B expanded in eudicots mainly through numerous gene duplication events; while those in Clade-A were also coupled with a few gene loss events.
Moreover, they are often part of large and complex protein families that have experienced numerous gene duplication and loss events during their evolutionary history, meaning that distinguishing between orthologues and paralogues is difficult and requires fastidious preliminary analyses.
Within metazoa, slipins have been subjected to numerous gene duplication events, and at least one gene fusion event with a sterol carrier protein that occurred prior to the divergence of protostomes and deuterostomes [ 17] and gave rise to SLP-1, now named slipin-1.
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Although the specifics of this case study probably do not apply generally to all lenses (for example, there is no evidence for numerous gene duplications of crystallins in some other species), we expect that generally similar mechanisms of co-option and duplication were important.
Their genetic evolution is very complex and includes numerous gene duplications (orthologous and paralogous in prokaryotes and eukaryotes), vast nucleotide change, and elaborate alternative splicing (Miller 2000; Anderson and Greenberg 2001; Sansom et al. 2002; Pichon et al. 2004; Hill et al. 2008).
We identified numerous gene duplications creating sets of orthologous and paralogous genes.
The evolutionary history of genomes combines vertical descent with numerous gene duplications and lineage-specific losses.
The R2R3-MYBs family has evolved and expanded very rapidly through numerous gene duplications in Angiosperms [ 36].
Because numerous gene duplications and gene losses occurred, we tried to reconcile the gene and species trees using Notung 2.6 [ 62].
This change in protein addressing was clearly accompanied by numerous gene duplications leading to 32 and 27 genes involved in starch synthesis in maize and rice [ 17].
Gene families in Lepidoptera encoding the structural chorion proteins are characterised by numerous gene duplications, occasional subsequent gene loss, gene conversion, and in general rapid sequence divergence [ 61, 179].
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